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Mega Curcumin

Mega Curcumin

Contains:

Curcumin extract with harpagophytum (grapple plant), ashwagandha, boswellia, and papaverine.

These herbs are known as helpful in dealing with Arthritis.

Contains 60 capsules.


No Preservatives & No Food Coloring


Harpagophytum procumbens

Harpagophytum is known as an anti-inflammatory and anti-rheumatic plant.

It is effective in treating arthritis and joint pain.


It is also effective in treating inflammation and pain in the musculoskeletal system, especially in the thighs, knees and lower back.


Boswellia

Boswellia is known as an anti-inflammatory plant. The use is in the Boswellia resin found under the peel of the plant.

Boswellia is effective in mitigating pain and treating arthritis, rheumatism and rheumatism.

In addition, Boswellia is effective against muscle pain and for the treatment of gout and fibromyalgia.




Further information about the product, including scientific references, can be found below




The stated above does not constitute a medical advice. Please consult your healthcare provider with any question or concerns you have on your medical condition.  


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Reviews




Noa’s testimonial


Hello,

My name is Noa Lezorovich and I use your Curcumin product.

I really enjoy the results. The pain in the palm's tendons has completely vanished so I can hold writing instruments very comfortably again. 

After I started taking two servings a day, the pain I had between my neck and shoulder greatly diminished, and I hope for further improvement later on.

I should also mention that I am less tired than before and my mood and energies have improved, probably because of the Ashuganda extract that the pill contains.


Thank you for the quick response I received when I called and for the clear and welcoming explanation I received when I contacted you.

Best,

Noa

Holon, Israel



Yelena's testimonial


Hello everyone!

This is my mother in law celebrating her 91th birthday!

Thanks to Nufar's Mega Curcumin she feels well. 

Best,

Yelena

Fanicea Nature Shop,  

050-9656456


Добрый день!

Моя свекровь Лидия празднует день рождения 91!

Благодаря Куркумин у от нуфар она чувствует себя прекрасно! 

Елена

Магазин "панацея" 

0509656456




Scientific studies on the effect of curcumin


The curcumin plant helps treat muscle aches and various infections, such as arthritis and inflammations resulting from increased exercise, and therefore can also help improve the recovery process among athletes and physically active people. These effects are attributed to the anti-inflammatory and antioxidant properties of curcumin. [1]

A study published in 2014 in the journal Phytotherapy Research examined the effect of curcumin (and other curcuminoids found in the curcumin plant) on arthritis in the knees. The researchers randomly divided 40 subjects into two groups. For six weeks, subjects in the treatment group received 1,500 mg of curcumin per day (in three doses of 500 mg), whereas subjects in the control group received the same dose of a placebo. Compared to the subjects in the control group, the findings showed a substantial and statistically significant decrease in the severity of arthritis and in the degree of the pain reported by the subjects who received the treatment. Although the differences between the groups in the degree of joint stiffness were not statistically significant, there was a significant improvement in physical function among the subjects in the treatment group. The conclusions of the study suggested that the use of curcuminoids extracted from the curcumin plant is an effective and safe treatment for arthritis.

 

Bibliography

[1] Hewlings, S.J. and Kalman, D.S., 2017. Curcumin: a review of its effects on human health. Foods6(10), p.92.


[2] Panahi, Y., Rahimnia, A.R., Sharafi, M., Alishiri, G., Saburi, A. and Sahebkar, A., 2014. Curcuminoid treatment for knee osteoarthritis: A randomized double‐blind placebo‐controlled trial. Phytotherapy Research, 28(11), pp.1625-1631.




The Medical Characteristics of Curcumin:


A bibliography by professor Reuven Or, Hadassah University Hospital, Ein Kerem, Jerusalem.  


Multiple Biological Activities of Curcumin: A Short Review. Radha K. Maheshwari et al. in Life Sciences, Vol. 78, pages 2081–2087; 2006.


The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease. Edited by Bharat B. Aggarwal, Young Joon Surh and Shishir Shishodia. Springer (in press).


Perkins S, Verschoyle RD, Hill K, Parveen I, Threadgill MD, Sharma RA, Williams ML, Steward WP, Gescher AJ. Chemopreventive efficacy and pharmacokinetics of curcumin in the min/+ mouse, a model of familial adenomatous polyposis. Cancer Epidemiol Biomarkers Prev. 2002; 11:535-40.


Dorai T, Cao YC, Dorai B, Buttyan R, Katz AE. Therapeutic potential of curcumin in human prostate cancer- curcumin inhibits proliferation, induces apoptosis, and inhibits angiogenesis of LNCaP prostate cancer cells in vivo. The Prostate 2001; 47: 293-303.


Korutla L, Kumar R. Inhibitory effect of curcumin on epidermal growth factor receptor kinase activity in A431 cells. Biochim. Biophys. Acta 1994; 1224: 597–600.


Korutla L, Cheung JY, Mendelsohn J, Kumar R. Inhibition of ligand-induced activation of epidermal growth factor receptor tyrosine phosphorylation by curcumin. Carcinogenesis 1995; 16: 1741–1745.


Piwocka K, Zablocki K, Wieckowski MR, Skierski J, Feiga I, Szopa J, Drela N, Wojtczak L, Sikora E. A novel apoptosis-like pathway, independent of mitochondria and caspases, induced by Curcumin in human lymphoblastoid T (Jurkat) cells, Exp.Cell Res. 1999; 299-307.



Research on Harpagophytum

 

The Harpagophytum procumbens (Hp) plant grows in the arid steppes of South Africa, Namibia and Botswana. For centuries, it has been used as a traditional treatment for a variety of illnesses, including fevers, skin problems, arthritis and digestive problems. Its use began to be popular throughout Europe in the early twentieth century for the treatment of various problems, including arthritis. Most animal studies have shown that the Hp plant effectively treats various infections. A number of clinical trials in humans have found that the Hp plant improved the condition of the subjects, relieved pain resulting from back and joint infections, and improved physical mobility. [1]

 

For example, in a study published in the journal Phytotherapy Research in 2003, the researchers recruited 75 subjects who suffered from arthritis in the knees and thighs and monitored their condition for 12 weeks in which each subject received a daily dose of the Hp plant (50 mg). At the end of the 12 weeks, the subjects showed a significant improvement of about 24.5% in the pain indices and an improvement in other symptoms related to arthritis such as the degree of stiffness and physical functioning. [2]

 

Despite the positive results, it is not possible to know with certainty that the treatment of the Hp plant was the factor that caused the improvement observed in the condition of the subjects. This is because there was no control group to which the condition of the treated patients could be compared in that study. In other words, there is some doubt that the same results might have been observed even if the subjects had not received the treatment. To remove this doubt to a large extent, a randomized controlled trial should be conducted.

 

Such a randomized controlled trial was conducted in a study published in 2001. [2,3] The researchers recruited 46 subjects and randomly assigned them into two groups. The treatment group received a daily dose of 30 mg of Hp for 20 weeks. The control group received a placebo at the same dose for the exact same period. The results of the experiment showed a substantial and statistically significant decrease in the level of pain and the demand for painkillers among subjects in the treatment group compared to those in the control group. Other randomized controlled trials have shown similar results: Treatment with the Hp plant has improved the condition of those suffering from various arthritis and back pain (see references 4 to 8 in the bibliography).

 

 

Bibliography

[1] Grant, L., McBean, D.E., Fyfe, L. and Warnock, A.M., 2007. A review of the biological and potential therapeutic actions of Harpagophytum procumbens. Phytotherapy Research, 21(3), pp.199-209.

 

[2] Wegener, T. and Lüpke, N.P., 2003. Treatment of patients with arthrosis of hip or knee with an aqueous extract of devil's claw (Harpagophytum procumbens DC.). Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 17(10), pp.1165-1172.

 

[3] Frerick, H., Biller, A. and Schmidt, U., 2001. Stufenschema bei coxarthrose. Der Kassenarzt, 5(34), p.41.

 

[4] Lecomte, A. and Costa, J.P., 1992. Harpagophytum dans l'arthrose: Etude en double insu contre placebo. Le Magazine, 15, pp.27-30.

 

[5] Fiebich, B.L., Heinrich, M., Hiller, K.O. and Kammerer, N., 2001. Inhibition of TNF-α synthesis in LPS-stimulated primary human monocytes by Harpagophytum extract SteiHap 69. Phytomedicine, 8(1), pp.28-30.

 

[6] Chantre, P., Cappelaere, A., Leblan, D., Guedon, D., Vandermander, J. and Fournie, B., 2000. Efficacy and tolerance of Harpagophytum procumbens versus diacerhein in treatment of osteoarthritis. Phytomedicine, 7(3), pp.177-183.

 

[7] Chrubasik, S., Junck, H., Breitschwerdt, H., Conradt, C. and Zappe, H., 1999. Effectiveness of Harpagophytum extract WS 1531 in the treatment of exacerbation of low back pain: a randomized, placebo-controlled, double-blind study. European Journal of Anaesthesiology, 16(2), pp.118-129.

 

[8] Göbel, H., Heinze, A., Ingwersen, M., Niederberger, U. and Gerber, D., 2001. Effects of Harpagophytum procumbens LI 174 (devil's claw) on sensory, motor und vascular muscle reagibility in the treatment of unspecific back pain. Schmerz (Berlin, Germany), 15(1), pp.10-18.


The stated above does not constitute a medical advice. Please consult your healthcare provider with any question or concerns you have on your medical condition.  



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